HLA B27 分型測試

What is ankylosing spondylitis?

Ankylosing spondylitis (AS) is a form of chronic inflammatory and degenerative arthritis which predominately affects the spinal and sacro-iliac joints. It is characterized by fused spinal bones, permanent painful stiffness and reduced flexibility of the back.

What genes are related to ankylosing spondylitis?

There are variations in several genes that increase the risk of developing ankylosing spondylitis. One of them is a variation of the HLA-B gene called HLA-B27. About 90 – 95 % of patients with AS are inherited with HLA-B27. However, most people with this version of the HLA-B gene never develop the disorder.

What is this test for?

This test detects the HLA-B27 variation of the HLA-B gene.

Who should consider this test?

  1. Individuals with signs and symptoms of ankylosing spondylitis as suggested by clinical findings

測試詳情

測試代碼
測試方法
樣本要求
測試所需時間
GHL
實時聚合酶鏈式反應(RT-PCR)
6毫升血(EDTA 管)
4 日

Rejection criteria

  • Specimen without proper labeling
  • Specimen not in requested format or insufficient quantity
  • Specimen in container expired for more than 1 month
  • Container leakage
  • Sampling date is more than 7 days
  • Frozen specimen, haemolysed or clotted blood specimen

Factor(s) known to affect results

  • Improper collection, handling and storage of specimen

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